Clinical Coordinating Center (CCC)

Dr. Barsan is Professor and former Chair of the Department of Emergency Medicine at the University of Michigan Medical School.  Dr. Barsan has been involved in stroke clinical trials since 1983. He led the development of an Emergency Medicine Residency at the University of Michigan and spear-headed the creation of the Department of Emergency Medicine within the medical school in 1999. His academic focus is translational research in stroke and neurological emergencies. He was an investigator in the initial pilot studies evaluating tPA in ischemic stroke and he was part of the team the designed the pivotal NINDS tPA trial as well as the NIH Stroke Scale. Since 2006, he has been the principal investigator of the Clinical Coordinating Center for the Neurological Emergencies Treatment Trials Network (NETT). In 2010, Dr. Barsan was also co-Principal Investigator on the ADAPT-IT (Accelerating Drug and Device Evaluation through Innovative Clinical Trial Design) project funded by NIH and FDA for advances in regulatory science. The ADAPT-IT project has been instrumental in promoting the use of adaptive clinical trial designs in confirmatory phase clinical trials and evaluating the advantages and barriers to adaptive design strategies.